40x Io Rune
Io Rune is the #16 of the 33 runes in Diablo 2: Resurrected, socketable into any item with an open socket for a flat stat bonus, or combined with other runes to build a runeword.
Key Stats
- Weapon: +10 Vitality
- Helm / Body Armor: +10 Vitality
- Shield: +10 Vitality
Why buy this
Buying Io Rune outright skips the farming or trading needed to find one naturally, which matters more the higher up the rarity order a rune sits. Combine three Hel Runes in the Horadric Cube to upgrade into one Io Rune (some tiers in this range also need a gem).
- Required for Memory, Dream
- Mid rune — worth comparing farming time against buying it directly
- Delivery options below show whether this rune is currently in stock
Quick Facts
- Rune order: #16 of 33
- Tier: Mid rune
- Required level: 35
- Weapon modifier: +10 Vitality
- Armor / helm modifier: +10 Vitality
- Shield modifier: +10 Vitality
FAQ
What is the order of D2R runes?
Runes are ordered by rarity from El (#1, most common) to Zod (#33, rarest), with required level increasing roughly alongside that order.
What does Io Rune do?
As a weapon modifier it gives +10 vitality. In a helm or body armor it gives +10 vitality, and in a shield it gives +10 vitality.
What runewords use Io?
Memory, Dream, among others.